2024-01-30

The Stories of Long COVID

 

To write or To Type is a question to brain connections
Long COVID: Immune Damage
 

 

 

 

 

 

 

 

 

 


Long COVID : synapse



Long COVID : microglia





Uncovering the Mystery of COVID-19 Brain Fog II: Microglia Betrayal : Sars-Cov-2 does not directly prune synapses, but activates microglia ...



Long COVID : dopamine





2024-01-28

Psalms in Wikidata | 維基數據中的詩篇 (29)

 Psalm 29 (Q1630080)  follows Psalm 28 (Q1630080)

Praise to God in His Holiness and Majesty
A Psalm of David.
 

Give unto the Lord, O you mighty ones,
Give unto the Lord glory and strength.
Give unto the Lord the glory due to His name;
Worship the Lord in the beauty of holiness.
The voice of the Lord is over the waters;
The God of glory thunders;
The Lord is over many waters.
The voice of the Lord is powerful;
The voice of the Lord is full of majesty.
The voice of the Lord breaks the cedars,
Yes, the Lord splinters the cedars of Lebanon.
He makes them also skip like a calf,
Lebanon and Sirion like a young wild ox.
The voice of the Lord divides the flames of fire.
The voice of the Lord shakes the wilderness;
The Lord shakes the Wilderness of Kadesh.
The voice of the Lord makes the deer give birth,
And strips the forests bare;
And in His temple everyone says, “Glory!”
The Lord sat enthroned at the Flood,
And the Lord sits as King forever.
The Lord will give strength to His people;
The Lord will bless His people with peace.


29 ( 大 衛 的 詩 。 ) 

1 神 的 眾 子 啊 , 你 們 要 將 榮 耀 、 能 力 歸 給 耶 和 華 , 歸 給 耶 和 華 !
2 要 將 耶 和 華 的 名 所 當 得 的 榮 耀 歸 給 他 , 以 聖 潔 的 ( 的 : 或 譯 為 ) 妝 飾 敬 拜 耶 和 華 。
3 耶 和 華 的 聲 音 發 在 水 上 ; 榮 耀 的 神 打 雷 , 耶 和 華 打 雷 在 大 水 之 上 。
4 耶 和 華 的 聲 音 大 有 能 力 ; 耶 和 華 的 聲 音 滿 有 威 嚴 。
5 耶 和 華 的 聲 音 震 破 香 柏 樹 ; 耶 和 華 震 碎 利 巴 嫩 的 香 柏 樹 。
6 他 也 使 之 跳 躍 如 牛 犢 , 使 利 巴 嫩 和 西 連 跳 躍 如 野 牛 犢 。
7 耶 和 華 的 聲 音 使 火 燄 分 岔 。
8 耶 和 華 的 聲 音 震 動 曠 野 ; 耶 和 華 震 動 加 低 斯 的 曠 野 。
9 耶 和 華 的 聲 音 驚 動 母 鹿 落 胎 , 樹 木 也 脫 落 淨 光 。 凡 在 他 殿 中 的 , 都 稱 說 他 的 榮 耀 。
10 洪 水 泛 濫 之 時 , 耶 和 華 坐 著 為 王 ; 耶 和 華 坐 著 為 王 , 直 到 永 遠 。
11 耶 和 華 必 賜 力 量 給 他 的 百 姓 ; 耶 和 華 必 賜 平 安 的 福 給 他 的 百 姓 。


 

2024-01-25

Have a cup of coffee to “seal” Sars-Cov-2 for 6 hours

中文版

Part I: Scientific progress & Basic Proteases

Whether you are a ground, instant, or caffeine-free coffee lover, recent science has brought good news. Ingredients in coffee, such as caffeine, chlorogenic acid, and isochlorogenic acid, can help us reduce infection with Sars-Cov-2 risks [1]. Drinking coffee helps block the entry of Sars-Cov-2 into host cells, and this blocking seal includes most variants such as Alpha, Delta and Omicron. This “coffee barrier”(Coffee Kekkai / 咖啡結界) is completed by the interaction of coffee components with different proteases in host cells, thereby achieving mechanisms such as inhibiting the binding and reducing the activity of cells and Sars-Cov-2 . ...

Part II : Coffee’s Collaborative Protection and Unknown Ingredients

 

Reference:

[1]News-Medical.Net: Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy, 2023-11-16, https://www.news-medical.net/news/20231116/Coffee- and-COVID-Study-finds-coffee-inhibits-SARS-CoV-2-offers-new-dietary-defense-strategy.aspx .

[2] Vu, T. H. T., Rydland, K. J., Achenbach, C. J., Van Horn, L., & Cornelis, M. C. (2021). Dietary behaviors and incident COVID-19 in the UK Biobank. Nutrients, 13(6), 2114.

[3] Wu, C. S., Li, Y. C., Peng, S. L., Chen, C. Y., Chen, H. F., Hsueh, P. R., ... & Hung, M. C. (2023). Coffee as a dietary strategy to prevent SARS-CoV-2 infection. Cell & Bioscience, 13(1), 210.

[4] Vargas-Alarcón, G., Posadas-Sánchez, R., & Ramírez-Bello, J. (2020). Variability in genes related to SARS-CoV-2 entry into host cells (ACE2, TMPRSS2, TMPRSS11A, ELANE, and CTSL) and its potential use in association studies. Life Sciences, 260, 118313.

Jackson, CB, Farzan, M., Chen, B., & Choe, H. (2022). Mechanisms of SARS-CoV-2 entry into cells . Nature reviews Molecular cell biology , 23(1), 3-20.

[5] U.S. National Library of Medicine ACE2 : https://www.ncbi.nlm.nih.gov/gene/59272

Turner, AJ, & Nalivaeva, NN (2022). Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation . Peptides , 151, 170766.

[6] U.S. National Library of Medicine TMPRSS2 : https://www.ncbi.nlm.nih.gov/gene/7113

Jackson, C. B., Farzan, M., Chen, B., & Choe, H. (2022). Mechanisms of SARS-CoV-2 entry into cells. Nature reviews Molecular cell biology, 23(1), 3-20.

Epstein, R. J. (2021). The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor. Tumor Biology, 43(1), 159-176.

[7] 美國國家醫學圖書館CTSL : https://www.ncbi.nlm.nih.gov/gene/1514

Weiss-Sadan, T., Itzhak, G., Kaschani, F., Yu, Z., Mahameed, M., Anaki, A., ... & Blum, G. (2019). Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation [S]. Molecular & Cellular Proteomics, 18(7), 1330-1344.

Zhao, Miao-Miao, et al. "Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies." Cell Discovery 8.1 (2022): 53.

[8] Romero-Martinez, B. S., Montano, L. M., Solis-Chagoyan, H., Sommer, B., Ramirez-Salinas, G. L., Perez-Figueroa, G. E., & Flores-Soto, E. (2021). Possible beneficial actions of caffeine in SARS-CoV-2. International Journal of Molecular Sciences, 22(11), 5460.

[9] Sci.News. Coffee Compound Reduces Binding of SARS-CoV-2 Virus to Its Human Target, Study Shows, Nov.15, 2022. https://www.sci.news/medicine/coffee-compound-sars-cov-2-virus-11391.html

[10] Ahvanooei, M. R., Norouzian, M. A., & Vahmani, P. (2021). Beneficial effects of vitamins, minerals, and bioactive peptides on strengthening the immune system against COVID-19 and the role of cow’s milk in the supply of these nutrients. Biological trace element research, 1-14.

[11] Sumimura Yoshimori is the protagonist of the well-known manga / anime " Boundary Master " . He likes to drink coffee and milk on weekdays .

 


 

喝杯咖啡,協力封印新冠六小時

 





 喝杯咖啡,協力封印新冠六小時 , 方格子: